2-Amino-3,5-dibromobenzaldehyde [CAS No. : 50910-55-9]

IUPAC Name 2-Amino-3,5-Dibromobenzaldehyde (ABDA)
CAS Number 50910-55-9
Molecular Formula C7H5Br2NO
Molecular Weight 220.27u
Melting Point 130-135 C
Purity 98-99%
Product ID: AL-001 Category:
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Description

2-Amino-3,5-dibromobenzaldehyde has been identified as one of the oxidation product of bromhexine by controlled potential electrolysis followed by HPLC-UV and GC-MS. It participates in the Friedländer condensation of C-β−glycosylic ketones to form 2-substituted quinoline derivatives.

Application

2-Amino-3,5-dibromobenzaldehyde may be employed in the preparation of tetradentate Schiff base ligands, via condensation with aliphatic diamines. These ligands forms nickel (II) and oxovanadium(IV) complexes.
2-Amino-3,5-dibromo-benzaldehyde (Bromhexine EP Impurity B) reagent used in the preparation of Ambroxol and Bromhexine (B678600) metabolites Ambroxol EP Impurity E.
END USE API –
  1. Ambroxol Hydrochloride
  2. Bromhexine
  3. Acebrophylline
Chemical Name 2-Amino-3,5-dibromo-benzaldehyde
Synonyms 2-Amino-3,5-dibromobenzaldehyde; 3,5-Dibromo-2-aminobenzaldehyde; Bromhexine EP Impurity B; Ambroxol EP Impurity E;
Impurity Bromhexine EP Impurity B
CAS Number 50910-55-9
Molecular Formula C₇H₅Br₂NO
Appearance Yellow Solid
Melting Point 132-134°C
Molecular Weight 278.93
Storage -20°C
Solubility Chloroform (Slightly), Methanol (Slightly)

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